早期结肠直肠瘤的切除使用内镜下粘膜解剖:一个回顾性的多中心队列研究
Katarzyna Winter1, Przemysław Kasprzyk1, Zuzanna Nowicka2
1Center of Bowel Treatment, 95-060 Brzeziny, Poland.
Journal of clinical medicine
|November 27, 2024
概括
内镜下粘膜切割 (ESD) 对于早期结直肠癌是有效的,提供高切割率. 虽然在直肠中成功,但在右结肠中的ESD需要更多的注意,因为并发症风险更高.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内镜手术 进行内镜手术
背景情况:
- 内镜下粘膜切割 (ESD) 是早期结肠直肠癌手术的最小入侵替代方案.
- 在特定的条件下,ESD提供一种潜在的治愈治疗选择.
- 分析影响ESD有效性的因素对于改善患者的治疗结果至关重要.
研究的目的:
- 调查影响内镜下粘膜切割 (ESD) 早期结直肠癌成功的因素.
- 确定成功切除和并发症的预测因素.
- 优化ESD技术,提高治疗早期结直肠瘤的疗效.
主要方法:
- 这是一项多中心的回顾性队列研究,涉及214名患者.
- 从2016年1月到2023年10月收集的数据.
- 对手术结果的分析,包括块切除,R0切除,治愈切除率和并发症发生率.
主要成果:
- 实现了高分块 (92.1%) 和R0切除 (69.6%) 的比率.
- 与结肠相比,直肠瘤 (81.4%) 的R0切除更频繁 (64.9%右, 61.1%左).
- 在15%的病例中出现并发症,在右结肠ESD手术中观察到的整体并发症和穿孔率更高.
结论:
- 内镜下粘膜切割 (ESD) 是早期结直肠癌的可行和有效的策略.
- 在直肠中的ESD显示出优异的结果.
- 右结肠中的ESD虽然有效,但由于增加并发症风险,需要精细的技术.
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