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在体外胆固醇的摄取由选定的头初始化作物的微生物群
Małgorzata Ziarno1, Dorota Zaręba2, Iwona Ścibisz1
1Department of Food Technology and Assessment, Institute of Food Science, Warsaw University of Life Sciences-SGGW (WULS-SGGW), Nowoursynowska 159c St., 02-776 Warsaw, Poland.
Life (Basel, Switzerland)
|November 27, 2024
概括
在模拟消化过程中,开起始培养物显示胆固醇结合减少. 有效的益生菌需要高胆固醇结合和通过消化道生存,以控制胆固醇.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 营养保健品 营养保健品
背景情况:
- ,一种发酵乳制品,以其潜在的健康益处而闻名,包括降低胆固醇.
- 益生菌的有效性受到胃肠道内的生存和功能的影响.
- 评估益生菌的性能需要在模拟的消化条件下进行评估.
研究的目的:
- 在实验室和模拟胃肠道条件下,评估精选的开起始培养物 (乳球菌和酵母菌) 的胆固醇结合能力.
- 为了比较这些培养在生长和模拟消化汁模型中的表现.
- 确定有效的益生菌配方用于胆固醇管理的关键特征.
主要方法:
- 在生长中培养乳球菌株和酵母.
- 在生长和模拟消化汁模型中评估胆固醇结合能力.
- 在模拟的消化环境中评估微生物生存率.
主要成果:
- 在模拟的胃肠道条件下,包括乳球菌和酵母在内的精选的凯菲尔初始培养表明胆固醇结合能力降低.
- 乳球菌株在实验室和模拟消化环境之间显示了胆固醇结合的显著差异.
- 酵母培养物在中显示了较高的胆固醇结合,但在消化模型中生存能力有限.
结论:
- 这项研究强调了仅仅依赖实验室条件来预测益生菌功能的局限性.
- 对于胆固醇管理,有效的益生菌配方需要具有高胆固醇结合能力和强大的胃肠道存活能力的菌株.
- 建议对酵母菌株及其机制进行进一步研究,以开发改进的益生菌干预措施.
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