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在雄性大鼠中对Regorafenib和青之间的相互作用进行药理动力学研究

Agnieszka Karbownik1, Danuta Szkutnik-Fiedler1, Filip Otto1

  • 1Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, 60-806 Poznań, Poland.

Pharmaceutics
|November 27, 2024
PubMed
概括

降醇显著增加了对regorafenib的暴露,可能会恶化副作用. 雷戈拉菲尼布降低了青的水平,可能减少了癌症患者的止痛效果.

关键词:
药物 药物相互作用帕拉西托摩尔是一种可怕的药物.药物动力学 药物动力学雷戈拉芬尼布的使用情况

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