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Updated: Jun 6, 2025

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance
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工程pH和温度触发的药物释放与金属有机框架和脂肪酸

Wanying Wei1, Ping Lu1

  • 1Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08028, USA.

Molecules (Basel, Switzerland)
|November 27, 2024
PubMed
概括

研究人员开发了核心外微粒,使用热性伊米达酸框架-8 (ZIF-8) 和相变材料 (PCM) 进行双刺激药物递送. 这些颗粒可以在pH值和温度变化的反应中准确,触发性释放治疗药物.

关键词:
同轴电气喷雾器同轴电气喷雾器核心外微粒的核心外微粒.阶段变换材料的相变材料.药物输送是对刺激有反应的.泽奥利特式 伊米达索酸 框架-8-8

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Extraction: Advanced Methods00:56

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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