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Updated: Jun 6, 2025

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Published on: June 20, 2014

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Pd催化芳香双 C-H 化和内分子循环:获取林替代的基单元素

Hongke Xu1,2, Yuchen Yang1,2, Fei Li1,2

  • 1State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Gaohai Road, Guiyang 550014, China.

Molecules (Basel, Switzerland)
|November 27, 2024
PubMed
概括

研究人员开发了一种新的催化反应,用于合成类基化合物. 这种高效的方法形成了三种新的键,在温和的条件下创建复杂的基单体结构.

关键词:
通过C-H的化.双向定向系统是指向定向的系统.循环化 循环化氧化物异印多隆的化合物帕拉催化剂的催化作用

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All ortho–para directors, excluding halogens, are activating groups. These groups donate electrons to the ring, making the ring carbons electron-rich. Consequently, the reactivity of the aromatic ring towards electrophilic substitution increases. For instance, the nitration of anisole is about 10,000 times faster than the nitration of benzene. The electron-donating effect of the methoxy group in anisole activates the ortho and para positions on the ring and stabilizes the corresponding...
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