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从有抗糖尿病潜力的林果和葡萄中提升生物活性化合物的价值

Elena Neagu¹, Gabriela Paun¹, Camelia Albu¹

¹Centre of Bioanalysis, National Institute of Research and Development for Biological Sciences, 296 Splaiul Independentei, 060031 Bucharest, Romania.

Molecules (Basel, Switzerland)

|November 27, 2024

概括

农业工业的副产品,如葡萄和果果汁,可以产生有价值的生物活性多. 葡萄末提取物显示出强烈的酶抑制,这表明可持续应用的抗糖尿病潜力.

科学领域:

农业工业副产品价值化农业工业副产品价值化
生物活性化合物的绿色提取.
营养药品和药品中的应用.

背景情况:

越来越多的人对从农业废弃物中回收生物活性化合物的兴趣,以实现可持续管理.
果实加工产生大量的副产品,富含宝贵的化合物,如多.
这些副产品的价值化支持循环经济原则.

研究的目的:

通过使用绿色提取技术,从果和葡萄残渣中回收生物活性多.
评估提取物的酶抑制潜力,特别是针对α-氨酶和β-葡萄糖酶.
为了比较超声辅助提取 (UAE) 和加速溶剂提取 (ASE) 的疗效.

主要方法:

从 (Vaccinium vitis-idaea) 和葡萄 (Vitis vinifera) 果汁中提取聚醇,使用50%的乙醇通过阿联和ASE.
微过和超过的含有酒精的提取物.
使用UV-Vis光谱法和HPLC-PDA分析生物活性化合物;酶抑制试验 (α-氨酶,β-葡萄糖酶).

主要成果:

阿联和ASE都成功地回收了生物活性多.
提取物显示出明显的α-氨酶和β-葡萄糖酶的抑制.
葡萄末提取物与果末提取物相比,表现出更强的酶抑制,IC₅₀值接近于阿卡尔博斯标准.

结论:

农业工业果汁是具有抗糖尿病潜力的生物活性多的可行来源.
绿色提取方法,特别是ASE,对于获得强有力的酶抑制剂是有效的.
这些副产品的利用有助于可持续的废物管理和循环经济.

关键词:

它具有抗糖尿病潜力.生物活性化合物生物活性化合物副产品中的副产品.葡萄的葡萄汁是葡萄的葡萄汁.兰花果果汁的果汁.

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