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Updated: Jun 6, 2025

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非洲猪瘟病毒如何避开cGAS-STING途径?

Can Lin1,2,3,4, Chenyang Zhang1,2,3,4, Nanhua Chen1,2,3,4

  • 1College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.

Pathogens (Basel, Switzerland)
|November 27, 2024
PubMed
概括

非洲猪瘟病毒 (ASFV) 通过抑制干扰素基因 (STING) 循环GMP-AMP合成酶 (cGAS) 刺激途径来逃避宿主免疫力. ASFV蛋白质向cGAS,STING,TBK1,IKKε,IRF3和NF-κB等关键组件,以抑制抗病毒反应.

关键词:
非洲猪瘟病毒病毒检测DNA的感知能力刺痛是一种刺痛.cGAS 是一个气体.这是先天的免疫力.

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