Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

482
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
482

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Potential role of Akkermansia massiliensis in multiple sclerosis protection by the FcRL3 gene.

Genes and immunity·2026
Same author

Preventing frailty in multiple sclerosis is a realistic goal-Commentary.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Type 1 Diabetes and Multiple Sclerosis Share General Autoimmunity Genetic Variation.

Genes·2026
Same author

Reduced cyclin D3 expression in erythroid cells protects against malaria.

Nature·2026
Same author

Frailty across Neurological Diseases: Why Sex and Gender Matter.

Annals of neurology·2025
Same author

Evaluation of the Metabolomics Profile in Charcot-Marie-Tooth (CMT) Patients: Novel Potential Biomarkers.

Metabolites·2025

相关实验视频

Updated: Jun 6, 2025

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
04:55

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice

Published on: May 11, 2022

3.7K

酸对多发性硬化症的影响:证据和挑战

Lorena Lorefice1, Magdalena Zoledziewska2

  • 1Multiple Sclerosis Center, ASL Cagliari, Department of Medical Sciences and Public Health, Binaghi Hospital, University of Cagliari, via Is Guadazzonis 2, 09126 Cagliari, Italy.

Nutrients
|November 27, 2024
PubMed
概括

酸是一种肠道细菌的副产品,可以通过调节免疫系统和保护神经系统来帮助管理多发性硬化症 (MS). 需要进一步的临床试验来确认它对MS患者的有效性和安全性.

关键词:
这就是SCFAFA.饮食 饮食 饮食 饮食我们的肠道微生物群.多发性硬化症多发性硬化症酸 propionic 酸 的使用方法

更多相关视频

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.1K
Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.5K

相关实验视频

Last Updated: Jun 6, 2025

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
04:55

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice

Published on: May 11, 2022

3.7K
Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.1K
Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.5K

科学领域:

  • 神经免疫学 神经免疫学
  • 微生物组研究的研究.
  • 代谢障碍 代谢障碍 代谢障碍

背景情况:

  • 多发性硬化症 (MS) 是一种由免疫介导的中枢神经系统疾病,受环境因素的影响.
  • 肠道微生物组的改变和短链脂肪酸 (如酸) 的缺乏与MS病理有关.
  • 酸表现出与MS相关的潜在免疫调节和神经保护作用.

研究的目的:

  • 对酸在多发性硬化症中的作用的证据进行全面审查.
  • 分析酸补充剂在治疗多发性硬化症中的潜在益处.
  • 讨论使用酸作为MS补充疗法的挑战和局限性.

主要方法:

  • 对酸,肠道微生物组和多发性硬化症的研究进行文献综述.
  • 对酸对免疫和神经系统影响的临床前和临床数据的分析.
  • 评估拟议的作用机制,包括免疫调节和屏障完整性.

主要成果:

  • 酸具有免疫调节,神经保护和神经再生的特性.
  • 增加酸水平可以抵消炎症并改善MS中的屏障功能.
  • 潜在的好处包括直接调节免疫系统,减少肠道和血脑屏障的透性.

结论:

  • 补充 propionic 酸 显示承诺作为多发性硬化症的补充策略.
  • 进一步的大规模临床试验至关重要,以确定MS患者的疗效和安全性.
  • 澄清酸的作用可能导致MS管理的新型治疗方法.