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Updated: Jun 6, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

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从结构组合中识别和排名绑定站点:适用于SARS-CoV-2

Maria Lazou1, Ayse A Bekar-Cesaretli2, Sandor Vajda1,2

  • 1Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.

Viruses
|November 27, 2024
PubMed
概括

FTMove快速识别和排名病毒点上的潜在药物结合部位,帮助传染病药物发现和基于新兴病原体的结构设计.

关键词:
在FTMoveove中使用.这种药物针对SARS-CoV-2的药物目标.有约束力的场地评估.热点绘制地图结合性 结合性 结合性 结合性目标评估目标评估的目标.

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Conserved Binding Sites

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Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
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