超越抗病毒药物:长期COVID的替代疗法
Achilleas Livieratos1, Charalambos Gogos2, Karolina Akinosoglou2,3
1Independent Researcher, 15238 Athens, Greece.
Viruses
|November 27, 2024
概括
甲胺显示了治疗长期COVID (SARS-CoV-2感染的急性后续) 的最有证据. 对于其他非抗病毒疗法,如LDN和甲,需要进行更多的研究,以确认其有效性.
科学领域:
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 长期COVID或SARS-CoV-2感染 (PASC) 后急性后续,呈现病毒感染后持续的症状.
- 目前的PASC治疗正在发展,重点是非抗病毒策略.
研究的目的:
- 对长期COVID的非抗病毒疗法的证据进行审查.
- 识别PASC的知识差距和有前途的治疗方法.
主要方法:
- 覆盖范围审查方法.
- 从RCT,观察性研究和案例系列中映射证据.
- 评估的治疗方法包括甲胺,LDN,德克萨米他,他类药物,欧米茄-3s,L-阿尔金因,IVIg,和阿菲瑞斯.
主要成果:
- 甲胺显示了最强的临床证据,得到了大规模的第三期试验的支持.
- 在观察性研究中,低剂量纳尔特雷克松 (LDN) 和甲显示出有前景.
- 许多PASC疗法需要更强大的,大规模的临床试验来验证.
结论:
- 甲福明是长期COVID管理的主要非抗病毒候选药物.
- 进一步的研究对于确定PASC的疗效和指导临床实践至关重要.
- 新兴疗法需要调查,但需要更多的数据.
相关概念视频
Tumor Immunotherapy
480
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
480
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
Myocarditis III: Medical Management
2
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
2
COPD: Management Using Bronchodilators and Corticosteroids
179
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
179
Microorganisms in Medicine and Therapeutics
1
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1
Cancer Vaccines
340
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
340


