甲索基兰用于缓解烧伤患者的手术疼痛:一项前性单中心评估研究
Andreas Creutzburg1, Martin R Vestergaard1, Pernille Pape1
1Department of Anesthesiology, Center of Head and Orthopedics, Rigshospitalet, Copenhagen University Hospital, Inge Lehmanns Vej 6, Section 6011, DK-2100 Copenhagen, Denmark.
European burn journal
|November 27, 2024
概括
吸入的甲氧化是一种可行的选择,用于在更换连衣时管理烧伤患者的手术疼痛. 这项试点研究表明患者满意度很好,没有显著的不良事件,这表明了传统止痛药的潜在替代品.
科学领域:
- 疼痛管理 疼痛管理
- 烧伤护理 烧伤护理
- 麻醉学 麻醉学
背景情况:
- 烧伤患者的手术疼痛是一个重大的临床挑战.
- 通常用于缓解疼痛的阿片类药物具有呼吸抑制和恶心等风险.
- 甲氧氨酸是一种吸入麻醉剂,在医院前用于创伤疼痛.
研究的目的:
- 评估在医院环境中在烧伤包裹更换期间使用吸入式甲氧化治疗疼痛的可行性.
- 为了评估患者报告的疼痛水平,满意度和安全性,在methoxyflurane的管理.
- 为了比较患者和护士的疼痛评估,并监测不良影响.
主要方法:
- 试点研究涉及烧伤患者进行带更换.
- 主要结局:在0-100口头评分尺度上最大的过程性疼痛.
- 二次结果:患者满意度,护士疼痛评估,不良事件 (恶心,吐,咳,头痛) 和血液动力学监测.
主要成果:
- 包括12名患者;中位数最大的手术疼痛是60 (患者报告) 和57 (护士评估).
- 患者对美托西弗的满意度很高,平均得分为96.
- 副作用的发病率较低:一名患者报告咳,另一名患者经历了手术后的恶心;没有观察到显著的血液动力学变化.
结论:
- 吸入的甲氧化是一种可行的止痛选择,用于烧伤患者在医院环境中更换连衣时.
- 该药物表现出良好的耐受性和患者满意度.
- 甲氧化呈现出一种潜在的替代方案,用于手术疼痛管理在烧伤护理.
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