药品声明的有效性 确定长期护理设施中药物暴露的数据
Emma Pearce1, Geraint Rogers2,3, Lucy Carpenter2,3
1University of South Australia, UniSA Clinical & Health Sciences, Adelaide, Australia.
药品声明数据准确地反映了长期护理设施 (LTCF) 的药物使用情况. 90-120天的回顾期通常足以评估处方药的暴露.
科学领域:
- 药物监督 药物监督 药物监督
- 医疗信息学 医疗信息学
- 老年人药房 老年人药房
背景情况:
- 准确的药物数据对于长期护理设施 (LTCF) 的患者安全至关重要.
- 药品声明与实际药物管理之间的差异可能会影响护理质量和研究.
- 验证数据源对于可靠的药物暴露评估至关重要.
研究的目的:
- 评估LTCF中药物声明和药物管理图表数据之间的一致性.
- 为了确定使用药品声明来识别居民药物暴露的准确性.
主要方法:
- 一项前性队列研究的二次分析,涉及5个LTCF的279名居民.
- 药物管理图表与各种时间窗口 (0-180天) 内的药品索赔数据进行了比较.
- 解剖治疗化学物质 (ATC) 分类代码用于标准化药物数据; 计算了灵敏度,特异性和正预测值 (PPV).
主要成果:
- 在拥有完整数据的149名居民中,三位数的ATC药物的PPV在30天和180天的索赔窗口中超过了75%.
- 对于特定药物类,如糖尿病药物和心血管药物,使用120天窗口观察到高灵敏度 (≥90%).
- 大多数药物类别的特异性仍然很高 (≥85%),除了抗菌剂和止痛药.
结论:
- 药品主张数据表明,在评估LTCF中处方药的暴露时,其准确度很高.
- 90-120天的暴露窗口通常是充足的,尽管对于某些药物包装大小可能需要更长的时间.
- 索赔数据可以作为在这个人群中评估药物暴露的可靠工具.
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