使用系统性冠状动脉风险评估2 (SCORE2) 和系统性冠状动脉风险评估2-老年人 (SCORE2-OP) 算法对患有非功能性上腺瘤的患者进行心脏代谢风险评估
Marzena Jabczyk1, Justyna Nowak2, Sylwia Mielcarska3
1Department of Nutrition-Related Disease Prevention, Department of Metabolic Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia, Bytom, Poland.
概括
非功能性上腺腺瘤 (NFA) 患有高禁食葡萄糖的患者表现出更高的心血管疾病 (CVD) 风险. 腰部至部的比率和缩血压是NFA中心血管疾病的关键预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 非功能性上腺腺瘤 (NFA) 是与代谢障碍相关的常见瘤.
- 鉴于潜在的代谢并发症,评估NFA患者心血管疾病 (CVD) 风险至关重要.
研究的目的:
- 评估106名患有非功能性上腺腺瘤 (NFA) 的患者的心血管疾病 (CVD) 风险.
- 在NFA患者中利用SCORE2和SCORE2-OP算法进行心血管疾病风险分层.
- 为了确定这种人群中心血管疾病风险的代谢和人类学预测因素.
主要方法:
- 分析了106名患有NFA的患者.
- 用SCORE2和SCORE2-OP算法计算心血管疾病 (CVD) 的风险.
- 评估了人体测量测量 (包括腰比),代谢指数,脂质概况和碳水化合物代谢参数.
主要成果:
- 与低至中等风险组相比,在极高风险和高风险心血管疾病组中观察到更高的腰部至部比率 (WHR).
- 患有低至中等心血管疾病风险的患者的禁食葡萄糖水平明显低于高风险和非常高风险组.
- 在心血管疾病风险类别中,没有发现脂质参数或动脉质指数的显著差异.
结论:
- 禁食葡萄糖的升高与非功能性上腺腺瘤 (NFA) 患者心血管疾病风险的增加有显著关联.
- 系统性血压和腰比 (WHR) 是NFA中心血管疾病风险的成本有效预测指标.
- 在这个队列中,代谢指数在心血管疾病风险层之间没有显著差异.
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