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Updated: Jun 6, 2025

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice

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限量采样方法用于基于模型的达普托米辛精确剂量,以快速达到度-时间曲线下的目标区域:模拟研究研究

Tomoyuki Yamada1,2, Kazutaka Oda3, Masami Nishihara1

  • 1Department of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.

Basic & clinical pharmacology & toxicology
|November 27, 2024
PubMed
概括

优化达普托米辛的剂量需要有效的血液采样. 两点采样,包括C_trough,可以更快地达到度-时间曲线 (AUC) 下的目标区域.

关键词:
度-时间曲线下的面积.达普米辛是一种菌素.有限抽样有限的抽样.基于模型的精确剂量定量.治疗药物监测 治疗药物监测

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Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis12:41

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