腹部与冠状动脉结石化相比,以及黑人成年人心血管事件和死亡率的事件
Temidayo A Abe1, Fengxia Yan2,3,4, Titilope Olanipekun5
1Division of Cardiology, Department of Medicine (T.A.A.), Vanderbilt University Medical Center, Nashville, TN.
Circulation. Cardiovascular imaging
|November 27, 2024
概括
在预测黑人成年人的心血管事件方面,腹腔大动脉化 (AAC) 与冠状动脉 (CAC) 一样有效. 当CAC分数为零时,AAC可以提供有价值的风险评估.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 放射学 放射学是一门学科.
背景情况:
- 黑人成年人面临更高的心血管疾病 (CVD) 风险,通常被传统的冠状动脉 (CAC) 评分低估.
- 腹腔大动脉化 (AAC) 在CAC之前,可以更好地预测黑人成年人易患早期动脉样硬化的心血管疾病事件.
- 现有的风险计算器可能无法完全捕捉到这一群体中的心血管疾病风险.
研究的目的:
- 评估腹腔大动脉化 (AAC) 与冠状动脉 (CAC) 的预测价值,以评估心血管事件和黑人成年人的死亡率.
- 评估AAC和CAC在风险分层中的增量值,超出标准心血管风险算法.
- 为了研究AAC与心血管结果的关联,在个体中,CAC得分为零.
主要方法:
- 从杰克逊心脏研究 (JHS) 分析了2551名没有先前存在心血管疾病的参与者.
- 考克斯回归模型用于估计心血管事件和全因死亡率的危险比率.
- 评估了CAC和AAC的预测性能,无论是独立的还是被添加到池队列方程中,使用净重新分类指数.
主要成果:
- 在12.6年内,较高的CAC和AAC与心血管事件增加和全因死亡率有关.
- CAC和AAC的增量预测值与标准风险算法相比是可比的.
- 值得注意的是,45%的CAC得分为零的参与者具有可检测的AAC,并且AAC独立预测了这一亚组中的心血管事件.
结论:
- 腹腔大动脉化 (AAC) 显示出与冠状动脉 (CAC) 对心血管事件和黑人成年人死亡率的预测价值相当.
- AAC是评估心血管风险的宝贵工具,特别是在CAC分数为零的个体中.
- 这些发现强调了在对黑人成年人的综合风险评估中考虑AAC的重要性.
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