贝克抑郁症库存-II对初级甲状腺功能障碍症的甲状腺切除术后的反应:系统性审查和元分析
Om S Chitnis1, Sabrina K Wagner1, J Joseph Caraway2
1F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
初级偏甲状腺症 (pHPT) 患者在偏甲状腺切除术后显示出改善的抑郁症得分. 贝克抑郁症目录II得分为14或以上可能表明手术对pHPT有益.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 精神病学是一个精神病学.
背景情况:
- 初级甲状腺功能障碍症 (pHPT) 中的神经精神症状缺乏明确的外科手术指南.
- 抑郁症是影响pHPT患者生活质量的常见症状.
研究的目的:
- 系统地审查和分析贝克抑郁 inventory-II (BDI-II) 在pHPT患者在偏甲状腺切除术前后的得分.
- 评估副甲状腺切除术在改善pHPT患者抑郁症状方面的疗效.
主要方法:
- 在Embase,PubMed,Web of Science,PsycINFO和Ovid所有EBM评论中进行全面的文献搜索.
- 包含报告BDI-II评分的研究在pHPT患者的偏甲状腺切除术前和后.
- 对BDI-II得分进行元分析,以确定抑郁水平的变化.
主要成果:
- 在最初确定的1554项研究中,有9项研究符合纳入标准.
- 与对照组相比,pHPT患者的基线BDI-II得分明显高于对照组.
- 在手术后1个月和6个月观察到BDI-II得分的统计显著下降.
结论:
- 副甲状腺切除术导致pHPT患者抑郁症状显著改善.
- 贝克抑郁症目录II得分为14或以上可能是考虑在pHPT管理中进行甲状腺切除术的潜在指标.
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