早期精神病早期干预对自杀行为的影响-A元分析
Elkhan Tahmazov1, Jordan Bosse1, Benjamin Glemain2,3
1URCI University Hospital Department of Adult Psychiatry, Brest, France.
Acta psychiatrica Scandinavica
|November 27, 2024
概括
对精神病的早期干预显著减少了早期发病精神疾病的个体的三分之一的自杀死亡和自杀企图. 这一元分析强调了早期干预服务在预防自杀行为的关键作用.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 公共卫生 公共卫生
背景情况:
- 早期发病的精神障碍,包括前兆期和第一次发病精神病 (FEP),代表了自杀行为的一个关键时期.
- 精神病早期干预 (EIP) 旨在在这个高风险阶段及时提供治疗.
- 虽然EIP的有效性得到了认可,但对其对自杀行为的影响缺乏全面的分析.
研究的目的:
- 为了确定精神病早期干预是否会影响自杀死亡和尝试.
- 为了确定特定的干预方法,这些干预方法会影响这一群体的自杀行为.
主要方法:
- 根据PRISMA标准进行了系统的元分析.
- 在五个主要数据库 (PubMed,Cochrane,PsycINFO,Scopus,Embase) 中搜索到2023年2月20日之前发表的研究.
- 包括专注于EIP和自杀行为 (死亡或企图) 的研究,其主要结果是自杀死亡,次要是自杀企图.
主要成果:
- 该元分析包括来自2310个已识别的参考文献的9篇文章,检查了药物治疗,心理治疗和心理治疗等干预措施.
- 早期发病精神疾病的早期干预与自杀死亡 (OR=0.66,p=0.005) 和自杀企图 (OR=0.66,p=0.002) 的统计学上显著的三分之一减少有关.
- 结果仍然具有意义,在所有灵敏度分析中均有不显著的异质性,包括那些排除具有偏差高风险的研究.
结论:
- 早期干预计划对减少自杀死亡和早期发病精神障碍的尝试产生了显著的积极影响.
- 这一元分析是第一个整合了关于EIP对这一人口群中自杀风险的影响的证据.
- 全球实施和支持EIP服务对于全球早期干预和自杀预防至关重要.
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