平衡能力和感知能力之间的不协调与帕金森病中的跌倒有关:协调分析
Jason K Longhurst1, Andrew Hooyman2, Merrill R Landers3
1Department of Physical Therapy and Athletic Training, Saint Louis University, St. Louis, MO, USA.
Neurorehabilitation and neural repair
|November 27, 2024
概括
帕金森病患者 (PwPD) 如何平衡以及他们有多自信地这样做之间的差距预测下降. 解决这种不一致可能有助于降低PwPD的跌倒风险.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 康复科学 康复科学 康复科学
背景情况:
- 实际和感知平衡之间的关系与像跌倒这样的功能结果有关.
- 量化这种不一致及其对摔倒的影响需要进一步研究,特别是在特定人群中.
研究的目的:
- 开发一种用于量化平衡一致性/不一致性的新方法.
- 确定这种量化不一致性与帕金森病 (PwPD) 患者的跌倒史之间的关系.
主要方法:
- 来自五项研究的244名PwPD的综合数据.
- 衡量感知余额 (活动特定余额信心尺度;ABC) 和余额表现 (定时启动和启动;TUG).
- 用简单的线性回归来预测的ABC (基于TUG) 和报告的ABC之间的差异.
主要成果:
- 在对年龄,MDS-UPDRS第三部分,性别和TUG进行控制后,不一致性是跌倒状态的唯一显著预测因素 (OR=0.98,P=0.003).
- 将不一致性纳入模型显著提高了58%的预测准确性.
结论:
- 在PwPD的平衡不一致和跌倒历史之间存在显著的联系.
- 这种不一致是跌倒的独特预测因素,可能是预防跌倒策略的可修改目标.
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