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Updated: Jun 6, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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副麻醉口腔Dexmedetomidine对人类睡眠的影响:一个随机的,受控的药理动力学-药理动力学研究

Laura K Schnider1, Marta Ratajczak1, Rafael Wespi1

  • 1Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.

Anesthesiology
|November 27, 2024
PubMed
概括

新的口腔内甲基德克塞米丁 (DEX) 配方在治疗失眠方面表现有前途. 口腔DEX被快速吸收,改善了睡眠质量,在睡眠不良的人,并证明了有利的安全性,保证了进一步的临床研究.

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Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
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