美国,德国和瑞士新药推出和推出后的价格变化
Yannic Laube1,2, Miquel Serra-Burriel1,2,3, Camille C E G Glaus1,2
1Faculty of Law, University of Zurich, Zurich, Switzerland.
JAMA health forum
|November 27, 2024
概括
新药价格令人担忧. 在美国,癌症药物价格在推出后大幅上,与德国和瑞士不同,突出了对推出和推出后药物定价的政策关注的需要.
科学领域:
- 卫生经济学 卫生经济学
- 制药政策 制药政策
- 药品定价分析 药品定价分析
背景情况:
- 新药价格的上对医疗保健支出产生了重大关注.
- 了解推出后的价格动态至关重要,因为它们与最初的推出价格一起对药品总体支出做出了重大贡献.
研究的目的:
- 分析和比较美国,德国和瑞士新药的推出和推出后价格变化.
- 识别不同市场和治疗领域的药物定价趋势.
主要方法:
- 一项队列研究确定了2011年至2022年间美国FDA,EMA和Swissmedic批准的新药.
- 从2011年到2023年收集和分析了价格数据,包括发布价格和发布后的价格变化.
- 采用标准的统计方法来分析价格趋势随时间推移和不同国家的趋势.
主要成果:
- 美国新药推出价格从2011年到2022年大幅增加 (每年19.7%).
- 推出后,美国药物价格显著上 (10年后4.1%),特别是癌症药物.
- 相比之下,德国和瑞士在10年内经历了新药推出后的价格下降,癌症药物价格仍然较高,但与非癌症药物趋势相似.
结论:
- 美国推出后的药物价格,特别是癌症药物价格大幅上,与德国和瑞士观察到的趋势不同.
- 决策者在制定控制药物开支的战略时,必须考虑最初的推出价格和随后的推出后的价格上.
- 国际比较显示出不同的定价行为,这表明特定的市场因素会影响药品价格的变化.
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