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在喘患者中使用各种附加设备处理pMDI的用户友好性评估
Ahmed M Abdelfattah1, Rania M Sarhan2, Yasmin M Madney2
1Clinical Pharmacy Department, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Ras Sudr, 46612, Egypt.
AAPS PharmSciTech
|November 27, 2024
概括
单独使用计量剂量吸入器 (pMDIs) 对于喘患者来说很难正确使用. 间隔器显著改善了pMDI处理,而Able和Tips Haler设备需要更少的会话才能获得最佳的技术.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 制药技术 制药技术 制药技术
背景情况:
- 计量剂量吸入器 (pMDIs) 是常见的喘药物.
- 正确的吸入器技术对于有效的药物输送至关重要.
- 对于患者来说,使用pMDI可能是具有挑战性的,导致治疗不理想.
研究的目的:
- 在喘患者中评估单独使用pMDIs与使用各种间隔器的疗效.
- 确定影响正确吸入器技术学习曲线的因素.
- 为了比较与不同pMDI间隔器相关的易用性和处理错误.
主要方法:
- 150名喘患者在没有指导的情况下对pmdi技术进行了评估.
- 然后,患者接受了使用五种不同间隔器 (Aerochamber plus,Tips Haler,Able,Disposable,Aer-8) 的pMDIs的培训.
- 在演示后重新评估技术,直到达到最佳处理;记录了会话和错误的数量.
主要成果:
- 与使用间隔器的pMDIs相比,pMDI单独的处理错误在基线显著增加 (53.9%).
- 能够和提示的哈勒间隔器需要显著减少训练课程以获得最佳的技术.
- 在基线错误和患者人口统计学/认知得分之间发现了弱相关性.
结论:
- 间隔器简化了喘患者的pMDI使用.
- 不同的间隔器在处理难度和有效性方面有所不同.
- 能够的间距器证明了最少的处理步骤和最高的患者成功率没有协助.
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