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发生异胎妊娠的危险因素:系统审查和元分析

Ana Carolina Sarmento Brim¹, Victor Rivera Duran Barretto¹, José Guilherme Reis-Oliveira¹

¹Bahiana School of Medicine and Public Health, Salvador, Brazil.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

|November 27, 2024

概括

识别子宫外妊娠 (EP) 风险因素对于早期诊断和预防至关重要. 关键因素包括EP病史,盆腔炎症,不孕不育,之前的手术和输卵管绑定.

科学领域:

生殖健康生殖健康
妇科妇科医生妇科
流行病学流行病学

背景情况:

宫外妊娠 (EP) 对母亲健康构成重大风险,需要确定针对性干预的风险因素.
了解风险因素有助于早期诊断,改善结果,并制定EP的预防策略.

研究的目的:

系统地识别和分析与异胎妊娠 (EP) 发生相关的风险因素.

主要方法:

从2000年起,以英语和葡萄牙语出版的观察性研究的系统综述和元分析.
搜索了MEDLINE/PubMed,LILACS,Cochrane图书馆和虚拟健康图书馆,使用与异胎妊娠和风险因素相关的术语.
包括11项涉及25051名患者的研究,通过独立的数据提取和质量评估评估了16个潜在的风险因素.

主要成果:

在EP和EP史 (OR 9.03),盆腔炎症 (OR 4.00),不孕不育 (OR 3.70),腹部/盆腔手术 (OR 5.60) 和先前的输卵管绑架 (OR 5.59) 之间发现了强烈的关联.
较晚的孕产妇年龄 (30-34岁:OR 1.13; ≥40岁:OR 1.46),吸烟,多个伴侣,堕胎史和紧急避孕措施的使用显示出略有增加的风险.
口服避孕药的使用与风险降低有关 (OR 0.77),而避孕套的使用影响有限 (OR 0.93).

结论:

外胎妊娠 (EP) 强烈相关的风险因素凸显了有针对性的查政策的需要.
实施对已确定具有高风险因素的妇女进行查,可以改善早期发现和管理EP.

关键词:

异胎妊娠是一个异胎妊娠.女人的避孕方法不孕不育不孕不育不孕不育母亲的年龄孕产妇的年龄这是一个元分析.风险因素的风险因素是什么系统性审查系统性审查

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