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Updated: Jun 6, 2025

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发现了第一个BRD4第二原体 (BD2) -选择性抑制剂

Junhua Li1, Qingqing Hu1, Run Zhu1,2

  • 1China-New Zealand Joint Laboratory of Biomedicine and Health, State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Biocomputing, Institute of Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou 510530, China.

Journal of medicinal chemistry
|November 27, 2024
PubMed
概括

研究人员开发了首个向BRD4 BD2蛋白的选择性抑制剂,为表观遗传学研究提供了有前途的进步,并可能减少白血病治疗中的非向毒性.

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