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Updated: Jun 6, 2025

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
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Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes

Published on: September 25, 2013

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在Caenorhabditis elegans中,伊诺西六酸盐通路与RNA干扰和病原体防御相结合

Wenjing Xu1, Yifan Sun1, Peter Breen2,3

  • 1Institute of Future Agriculture, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China.

Proceedings of the National Academy of Sciences of the United States of America
|November 27, 2024
PubMed
概括

影响伊诺西六酸盐 (IP6) 合成的突变增强了C. elegans的RNA干扰 (RNAi) 抗病毒防御. 这种RNA编辑途径通常会调节siRNA抗病毒反应,影响病原体防御和展开的蛋白质反应信号.

关键词:
这是一种RNAi干扰.腺氨酸脱氨酶的使用.伊诺西六酸盐 伊诺西六酸盐不折叠的蛋白质反应反应

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