四年后的结果 肠内支离子AFLIBERCEPT用于患有病理性迷视的患者的黄斑新血管化
Yuka Mizuno-Onishi1, Tae Igarashi, Kengo Uramoto
1Department of Ophthalmology and Visual Science, Institute of Science Tokyo, Tokyo, Japan .
Retina (Philadelphia, Pa.)
|November 27, 2024
概括
在近视性黄斑新血管化患者中,静脉内射aflibercept注射维持了视力敏度4年. 这种治疗与疾病的自然过程相比,提供了视觉上的好处.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 新血管化的新血管化.
背景情况:
- 近视性黄斑新血管化 (MNV) 与视力敏度差相关.
- 抗血管内皮生长因子 (anti-VEGF) 药物显示对MNV的短期疗效.
- 对MNV抗VEGF治疗的长期结果至关重要.
研究的目的:
- 评估对近视性MNV的4年内内阿弗利塞普特注射的结果.
- 评估aflibercept在该患者群体中的长期安全性和有效性.
主要方法:
- 对49只近视MNV眼睛进行了回顾性单心研究.
- 通过预先推的治疗方案 (根据需要) 治疗静脉内阿弗利塞普特.
- 最低的随访时间为4年.
主要成果:
- 平均最佳校正视敏度 (BCVA) 在基线是20/45,在4年后是20/53.
- 平均每眼注射次数为1.6次.
- 与基线相比,在4年期间没有观察到BCVA的统计学上显著差异.
结论:
- 在近视性MNV患者中,使用pro re nata疗法进行的静脉肠道aflibercept治疗提供了为期4年的视觉效益.
- 这种治疗似乎优于疾病的自然过程,在4年内维持BCVA.
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