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Updated: Jun 6, 2025

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IFITM1通过通过增加AMPK-依赖的线粒体功能来促进NKT细胞激活来加剧ConA诱导的自身免疫性肝炎

Jie Sun1, Haozhe Xu1, Buer Li2

  • 1Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing 10020, China; Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.

International immunopharmacology
|November 27, 2024
PubMed
概括

干扰素诱导的跨膜1 (IFITM1) 蛋白对于自身免疫性肝炎 (AIH) 中的自然杀手T (NKT) 细胞功能至关重要. IFITM1的损失通过改善NKT细胞线粒体功能和生存来减少肝损伤.

关键词:
这就是AMPKK.自身免疫性肝炎的发生如果IFITM1是IFITM1,那么它就是IFITM1.线粒体中的线粒体.NKT 细胞 NKT 细胞

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