由真菌内细胞产生的核酸信号调节宿主细胞死亡,并促进根植殖
Nick Dunken1, Heidi Widmer2, Gerd U Balcke3
1Institute for Plant Sciences, University of Cologne, Cologne, Germany.
Cell host & microbe
|November 27, 2024
概括
有益的真菌Serendipita indica触发植物细胞死亡使用两个酶产生脱氧腺. 这种代谢物激活了植物的免疫路径,使真菌根植入和促进生长.
科学领域:
- 植物病理学 植物病理学
- 菌群学 菌群学 菌群学是指菌群学
- 植物免疫学 植物免疫学
背景情况:
- 有益的真菌Serendipita indica通过涉及宿主细胞死亡的双相策略来殖民植物根.
- 启动和控制这种植物细胞死亡的确切机制尚不清楚.
研究的目的:
- 阐明Serendipita indica诱导Arabidopsis thaliana根中的宿主细胞死亡的分子机制.
- 为了确定参与调节这一过程的真菌和植物因素.
主要方法:
- 生物化学分析检测酶活性和代谢物产生.
- 对真菌酶 (SiE5NT,SiNucA) 和植物受体 (ENT3,ISI) 的遗传分析.
- 显微镜和生理测量以评估真菌殖民和植物反应.
主要成果:
- 两个真菌酶,SiE5NT和SiNucA,在质细胞中协同产生脱氧腺素 (dAdo).
- 通过植物载体ENT3吸收脱氧腺酸激活细胞死亡.
- 一种新的植物TIR-NLR蛋白,ISI,被确定为细胞死亡,真菌殖民和生长促进的关键调节者.
结论:
- 酶活动产生一种代谢物 (dAdo),通过TIR-NLR通路触发植物细胞死亡.
- 这个过程将真菌诱导的免疫代谢与植物细胞死亡和殖民联系起来.
- 了解这些相互作用对于利用有益的真菌内细胞在农业中至关重要.
相关概念视频
01:28Yeast Signaling
14.4K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
14.4K
01:28Gene Regulation in Microbial Communities: Quorum Sensing
3
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
3
02:11The Roles of Bacteria and Fungi in Plant Nutrition
35.1K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
35.1K
01:29Fungal Group Zygomycota
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...