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对于下泌尿道症状的跨层激光切除后的对比增强超声波成像

R A A van Kollenburg¹, L A M J G van Riel¹, J R Oddens²

¹Urology, Amsterdam University Medical Center, Amsterdam, Netherlands; Biomedical Engineering and Physics, Amsterdam University Medical Center, Amsterdam, Netherlands.

|November 27, 2024

概括

跨膜激光切除 (TPLA) 创建不同的切除形状和体积,随着时间的推移显著减少前列腺大小. 然而,切除体积的患者间变异性会影响治疗的可预测性.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
最少侵入性的手术
医疗成像医学成像

背景情况:

良性前列腺增生 (BPH) 是一种常见的疾病,需要有效治疗.
跨膜激光切除 (TPLA) 是BPH的新兴微创治疗方法.

研究的目的:

在使用多种纤维配置的TPLA之后,以表征剥离区域的形状和体积.
为了在12个月内评估切除区域和前列腺体积的变化.
为了评估患者之间除体积的变异性.

主要方法:

对20名用EchoLaser系统接受TPLA的患者进行前性试点研究.
根据前列腺解剖学,利用了2-4根纤维.
与对比度增强的超声波 (CEUS) 在基线进行,在1个月和12个月进行体积计算.

主要成果:

切除区域可视化为CEUS上的非透区域,形状从圆到三叶草.
剥离量根据纤维数量和输送的能量有很大的差异.
平均前列腺体积在12个月内从78厘米缩至46厘米 (P=.0002).
前列腺体积的减少与Qmax和IPSS的改善相关.

结论:

TPLA有效地降低了前列腺体积,具有多种除区域特征.
治疗后观察到显著的前列腺体积减少.
切除体积的患者间变异性对治疗可预测性提出了挑战.

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