TFAP2C-DDR1轴调节乳腺癌中对CDK4/6抑制剂的耐药性

Muhammad Jameel Mughal1, Yi Zhang1, Zhuqing Li1

  • 1Department of Biochemistry and Molecular Medicine, GWU Cancer Center, George Washington University School of Medicine and Health Sciences, Washington, DC, 20037, USA.

Cancer letters
|November 27, 2024
PubMed
概括

研究人员发现了一种乳腺癌对CDK4/6抑制剂,如palbociclib.lib.,产生抗药性的新方法. 通过TFAP2C调节的DDR1通路的抑制可以使瘤对这种重要的治疗重新敏感.

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