用微/纳米技术增强的药物输送系统的3D打印
Hui Zhu1, Huijuan Kuang2, Xinxin Huang1
1State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710049, PR China; National Medical Products Administration (NMPA) Key Laboratory for Research and Evaluation of Additive Manufacturing Medical Devices, Xi'an Jiaotong University, Xi'an 710049, PR China; State Industry-Education Integration Center for Medical Innovations, Xi'an Jiaotong University, Xi'an 710049, PR China.
Advanced drug delivery reviews
|November 27, 2024
概括
本综述探讨了通过将微/纳米技术与3D打印相结合的先进药物递送系统 (DDS). 这些创新增强了药物安全性,有效性和向性交付,以改善治疗结果.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 制药科学 制药科学
背景情况:
- 药物输送系统 (DDS) 对于优化药物安全性和治疗疗效至关重要.
- 微/纳米技术使DDS具有增强的稳定性,生物可用性和有针对性的传递.
- 3D打印技术允许定制的DDS具有复杂的结构和多样化的组件.
研究的目的:
- 审查3D打印和微/纳米技术的整合,以开发新的DDS.
- 在DDS.中介绍3D打印机制的技术基础.
- 分析使用这些集成技术的DDS类型,以改善功能.
主要方法:
- 对3D打印机制 (例如挤出,喷墨,立体石版) 的当前研究进行审查.
- 在DDS中使用的微/纳米级材料和结构的分析.
- 检查通过3D打印和微/纳米技术实现的各种DDS设计.
主要成果:
- 3D打印有助于创建复杂的DDS架构,精确控制药物加载和释放.
- 3D打印的DDS中的微/纳米级组件增强了药物的稳定性,生物可用性和向性输送.
- 集成允许多功能DDS与量身定制的释放配置文件和提高治疗效率.
结论:
- 3D打印和微/纳米技术的协同作用为DDS设计和功能提供了显著的进步.
- 未来的方向侧重于技术创新和这些复杂的DDS的临床翻译.
- 这种跨学科的方法有望推动药物输送技术和患者治疗的进步.
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