在心力衰竭中使用可穿戴加速计测量身体活动:DETERMINE试验的见解
Kieran F Docherty1, Ruben Buendia Lopez2, Folke Folkvaljon3
1BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Journal of cardiac failure
|November 27, 2024
概括
可穿戴的加速度计为心力衰竭患者提供了一种测量身体活动的方法. 这些措施与功能限制评估的相关性很小,这表明它们可以提供补充数据.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 临床试验 临床试验
背景情况:
- 可穿戴的加速度计可以在日常生活中持续监测身体活动.
- 这些设备可能有助于评估心力衰竭患者的治疗疗效.
研究的目的:
- 探索加速计衍生体力活动与心力衰竭中功能限制的既定措施之间的关系.
- 为了在DETERMINE试验中调查左心室射出分数的整个频谱中的这些关联.
主要方法:
- 来自DETERMINE试验的319名患者的一个小组在7天内提供了基线加速度计数据.
- 患者完成了堪萨斯城心肌病问卷 (KCCQ) 和6分钟步行距离 (6MWD) 的评估.
- 在试验期间,在多个时间点收集了加速度计数据和功能测量.
主要成果:
- 较低的体力活动水平与较差的KCCQ分数和6MWD相关.
- 基线加速度计数据显示,KCCQ得分 (r=0.06-0.21) 和6MWD (r=0.20-0.31) 与KCCQ得分的相关性较弱至中等.
- 16周身体活动的变化与KCCQ分数 (r=0-0.18) 和6MWD (r=0.01-0.10) 的变化有很弱的相关性.
结论:
- 基于加速度计的体力活动测量显示,心力衰竭患者的KCCQ得分和6MWD与KCCQ得分之间存在温和的相关性.
- 这些可穿戴传感器评估可能会提供超越传统功能限制评估的补充见解.
相关概念视频
01:30Pulse rhythm
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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
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