内镜下粘膜道技术与Zenker分泌体的灵活内镜分泌切除术:一个系统的审查和元分析
Lucas Monteiro Delgado1, Gilmara Coelho Meine2, Paula Santo3
1Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Gastrointestinal endoscopy
|November 27, 2024
概括
与灵活的内镜分泌切除术 (FES) 相比,内镜分泌切除术 (ESTT) 在治疗Zenker的分泌管 (ZD) 方面取得了更高的临床成功. 这两种方法都为ZD管理提供了类似的安全和技术结果.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
背景情况:
- 禅克分泌管 (ZD) 是最常见的食道分泌管.
- 治疗方案包括内镜下粘膜道技术 (ESTTs) 和灵活的内镜隔膜切除术 (FES).
研究的目的:
- 系统地审查和比较ESTT与FES在ZD治疗中的有效性和安全性.
- 根据随访持续时间,分流体大小,使用的特定ESTT和出版格式进行子组分析.
主要方法:
- 来自PubMed,EMBASE和Cochrane图书馆数据库的研究的系统审查和元分析.
- 对连续结果 (平均差异) 和二进制结果 (风险比率) 的聚合分析,具有95%的置信区间.
- 使用I2统计数据评估的异质性.
主要成果:
- 包括9项涉及759名患者的研究.
- 与FES相比,ESTT显示临床成功的可能性更高 (RR,1.15;95% CI,1.04-1.28).
- 两种方法之间在临床复发,技术成功,手术时间,住院时间或不良事件方面没有发现显著差异.
结论:
- ESTT与治疗Zenker's分歧器的临床成功可能性更高有关.
- 无论是ESTT还是FES,都表现出可比的安全配置文件和技术成果.
- ESTT是一种有效和安全的内镜方法来管理ZD.
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