烟草吸烟,戒烟和心力衰竭亚型:来自杰克逊心脏研究的见解
Daisuke Kamimura1,2, Wondwosen K Yimer3, Robert J Mentz4
1Department of Medicine University of Mississippi Medical Center Jackson MS.
目前的吸烟增加了黑人成年人心力衰竭 (HF) 的风险. 长期戒烟,超过20年,对于将HF风险降低到与从不吸烟相比的水平至关重要.
科学领域:
- 心血管疾病流行病学
- 公共卫生 公共卫生
背景情况:
- 吸烟是心力衰竭 (HF) 的已知危险因素之一.
- 吸烟,戒烟和HF亚型之间的具体关联仍然不清楚,特别是在黑人人口中.
研究的目的:
- 为了调查吸烟,戒烟和发生HF住院治疗之间的关系.
- 为了检查与HF亚型的关联:黑人个体中HF与保留射出分数 (HFpEF) 和HF与减少射出分数 (HFrEF) 的HF.
主要方法:
- 对来自杰克逊心脏研究的4189名黑人参与者的分析,没有先前的HF或冠心病.
- 检查了当前吸烟,吸烟强度和吸烟负担与事件HF及其亚型的关联.
- 评估了戒烟时间对HF风险的影响.
主要成果:
- 与从未吸烟相比,目前的吸烟与两种HF亚型的风险增加有关.
- 更高的吸烟强度和负担与更高的HFpEF发生率相关.
- 需要超过20年的戒烟才能使HF风险正常化.
结论:
- 烟草吸烟独立地与发展两种HF亚型有关,无论基线肺功能如何.
- 持续的,长期的戒烟是防止吸烟者患上HF发病的关键.
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