Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

482
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
482
Neural Regulation01:37

Neural Regulation

39.1K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Increasing forest disturbance enhances habitat suitability for Europe's large herbivores.

Nature ecology & evolution·2026
Same author

Preprocessing on the Go: Practices in Gait-Related Mobile EEG.

Psychophysiology·2026
Same author

Steps against the burden of Parkinson's disease (StepuP): Protocol of a randomized controlled trial elucidating the biomechanical and neurophysiological mechanisms of a speed dependent treadmill training intervention.

PloS one·2026
Same author

Correction: How pain intensity and mental disorders shape chronic pain sick leave and quality of life in the general Spanish population.

Scientific reports·2026
Same author

ActiTect: a generalizable machine learning pipeline for REM sleep behavior disorder screening through standardized actigraphy.

NPJ digital medicine·2026
Same author

Whole body analysis of functional communities and topological features of gait with different speeds in Parkinson's disease.

Journal of neurology·2026
Same journal

Correction: A method for supervoxel-wise association studies of age and other non-imaging variables from coronary computed tomography angiograms.

Scientific reports·2026
Same journal

Poly(bromophenol blue)/CoSn(OH)<sub>6</sub> cubic particles modified pencil graphite electrode for electrochemical determination of diphenhydramine.

Scientific reports·2026
Same journal

Dietary Chlorella, Spirulina, and acidifier modulate jejunal cytokine-related gene expression in broiler chickens.

Scientific reports·2026
Same journal

Perceived physical activity barriers in university students: associations with fatigue and eating behaviours.

Scientific reports·2026
Same journal

Refuge limitation structures habitat use in agricultural landscapes: evidence from Sunda pangolins.

Scientific reports·2026
Same journal

Lightweight stateless transaction verification with outsourced witness updates for UTXO blockchains.

Scientific reports·2026
查看所有相关文章

相关实验视频

Updated: Jun 6, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.1K

从帕金森病中的行走特征预测执行功能,使用机器学习.

Artur Piet1, Johanna Geritz2, Pascal Garcia3

  • 1Institute of Medical Informatics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany. ar.piet@uni-luebeck.de.

Scientific reports
|November 28, 2024
PubMed
概括
此摘要是机器生成的。

这项研究揭示了帕金森病患者的步行模式和他们的执行功能之间的联系. 特定的步行特征,如步骤时间变化,与认知表现有显著的相关性.

关键词:
执行职能 执行职能 执行职能机器学习是机器学习.帕金森病是帕金森氏症的一种疾病.步行特征 步行特征 步行特征

更多相关视频

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
04:08

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

Published on: January 18, 2021

2.7K
Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K

相关实验视频

Last Updated: Jun 6, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.1K
Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease
04:08

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

Published on: January 18, 2021

2.7K
Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K

科学领域:

  • 神经学 神经学
  • 生物医学工程 生物医学工程
  • 老年病的医生 老年病的医生

背景情况:

  • 帕金森病 (PD) 呈现出运动和认知障碍.
  • 现有的研究表明,在PD中,运动症状 (行走) 和认知缺陷之间存在联系,但经验证据有限.
  • 了解这种关系对于全面的PD管理至关重要.

研究的目的:

  • 研究帕金森病患者的特定步行特征与执行功能之间的关联.
  • 应用先进的机器学习技术来分析步态数据和认知测试结果.
  • 确定可能作为PD认知状态生物标志物的步态参数.

主要方法:

  • 通过使用惯性测量单元 (IMU) 来分析103名老年帕金森病住院患者在四种行走条件下的步态数据.
  • 使用了五种归算方法和四种回归方法,包括链式方程多重归算 (MICE) 和支向量回归 (SVR).
  • 通过使用Trail-Making Test (TMT) 来评估执行职能.

主要成果:

  • 支持向量回归 (SVR) 结合连锁方程多重推算 (MICE) 提高了预测准确度4.95%.
  • 步行特征,特别是步行时间的变化,双肢支时间的变化,以及双任务行走时的步行速度与认知需求,与执行功能 (Δ-TMT) 的变化显著相关.
  • 仅使用步行特征的机器学习模型显示了与执行功能结果的显著,尽管轻微的相关性.

结论:

  • 这项研究提供了直接的经验证据,将特定的步态特征与帕金森病中的执行功能联系起来.
  • 步行特征,特别是在认知要求高的条件下,可以提供对PD患者认知状态的见解.
  • 这些发现强调了使用步态分析作为评估帕金森病认知功能的非侵入性工具的潜力.