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在CYP2B6多态和非核酸逆转录酶抑制剂之间存在关联:药物诱导的肝损伤:系统性审查和元分析

Noppadol Chanhom1, Janjira Sonjan1, Jarupat Inchai1

  • 1Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand.

Scientific reports
|November 28, 2024
PubMed
概括

在CYP2B6的遗传变异影响抗逆转录病毒药物诱导的肝损伤 (ARVDILI) 的风险从非核糖逆转录酶抑制剂. 特定的CYP2B6多态增加EFV诱导的肝损伤风险,但降低NVP诱导的肝损伤风险.

关键词:
在CYP2B6B6中.有不良影响的不良影响.药物诱导的肝损伤是药物诱导的遗传多形态的遗传多形态.肝毒性 肝毒性 肝毒性人类免疫缺陷病毒人类免疫缺陷病毒进行元分析分析.系统性审查 系统性审查

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