对患有精神障碍的父母的预防性干预与任何对照干预进行系统审查的协议,并对后代的结果进行元分析和试验顺序分析
Emilie Hestbaek1,2, Jeanne Kofoed3, Jane Barlow4
1Stolpegaard Psychotherapy Centre, Mental Health Services, Capital Region of Denmark, Stolpegaardsvej 20, Gentofte, 2820, Denmark. emilie.hestbaek.jacobsen@regionh.dk.
Systematic reviews
|November 28, 2024
概括
患有精神障碍的父母的预防性干预可以使他们的孩子受益,但需要对有效性和危害的全面证据. 这次系统审查将评估这些干预措施,以指导临床决策和未来的研究.
科学领域:
- 儿童和青少年精神病学 儿童和青少年精神病学
- 公共卫生 公共卫生
- 心理学 心理学 心理学
背景情况:
- 患有精神障碍的父母的孩子面临着不利后果的高风险.
- 关于预防性干预对这些儿童的益处和危害的现有证据是不确定的.
- 一个全面的概述对于为干预和政策提供信息至关重要.
研究的目的:
- 系统地审查和对心理障碍的父母预防干预措施对后代结果的影响进行元分析.
- 评估这些干预措施的有益和有害影响.
- 为临床医生,政策制定者和研究人员提供基于证据的指导.
主要方法:
- 使用元分析进行系统审查,遵守PRISMA指南.
- 使用柯克兰偏见风险工具 (ROB2) 进行偏见评估.
- 包括已公布和未公布的随机临床试验;评估主要结果 (生活质量,精神障碍发病率) 和后代的二次/探索性结果.
主要成果:
- 本部分应在研究完成后填写.
结论:
- 迫切需要对父母患有精神障碍的孩子的预防性干预措施进行全面审查.
- 结果将为有关有效干预措施的决策提供信息,并指导未来的研究.
- 基于证据的信息对于这种高度流行的人群至关重要.
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