Ezh2 在正常大脑颗粒神经元发育和中枢细胞瘤中延迟了差异化基因的激活

James Purzner1,2,3, Alexander S Brown3,4, Teresa Purzner1,2,3

  • 1Division of Neurosurgery, Department of Surgery, Queen's University, Kingston, ON.

概括

儿童脑髓母细胞瘤 (MB) 的差异化疗法可以通过向Ezh2.2来增强. 抑制Ezh2和迫使细胞周期退出同时促进MB细胞的神经元分化.

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