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Updated: Jun 6, 2025

Bulk Droplet Vitrification for Primary Hepatocyte Preservation
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在人体器官尺度上进行物理玻璃化和纳米加热,以实现冷保存

Lakshya Gangwar1, Zonghu Han1, Cameron Scheithauer1

  • 1Department of Mechanical Engineering, University of Minnesota, Minneapolis, USA.

bioRxiv : the preprint server for biology
|November 28, 2024
PubMed
概括

器官储存更接近现实,因为研究人员证明了玻璃化和重新加热大量器官,包括猪肝. 这一突破为未来的人体器官储存和移植铺平了道路.

关键词:
结冷保存是一种冷保存.人类器官 人类器官一升的体积.纳米变暖的使用方法玻璃化是一种玻璃化过程.

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Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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