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Updated: Jun 6, 2025

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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Published on: March 29, 2019

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在小鼠胚胎干细胞中,Lrif1调节了Trim28介导的Dux位点的抑制

Darina Šikrová, Román González-Prieto, Alfred C O Vertegaal

    bioRxiv : the preprint server for biology
    |November 28, 2024
    PubMed
    概括

    面骨肌缩症2型 (FSHD2) 涉及表观遗传变化. 通过与TRIM28相互作用,LRIF1蛋白有助于抑制DUX4 (与FSHD2相关的基因),保持肌肉健康.

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    Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands05:48

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