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Updated: Jun 6, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

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确定MRTFA/SRF通路作为癌症静止的关键调节器

Santiago Panesso-Gómez1, Alexander J Cole1, Alyssa Wield1

  • 1Department of Internal Medicine and Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA.

bioRxiv : the preprint server for biology
|November 28, 2024
PubMed
概括

癌症中的化学抵抗可以由细胞静止驱动. 使用CCG257081准肌肉糖相关转录因子/血清反应因子 (MRTF/SRF) 途径,可以抑制癌细胞静止和瘤生长.

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