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放射治疗对血液性恶性瘤的突变性影响和进化影响

Benjamin Diamond1, Dhanvantri Chahar2, Michael D Jain3

  • 1Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.

bioRxiv : the preprint server for biology
|November 28, 2024
PubMed
概括

放射疗法 (RT) 和化疗可以导致DNA损伤,导致ID8突变在复发性血液癌症中的突变特征. 通过全基因组测序检测到的这种特征,可以将复发的起源追溯到单个耐药细胞.

关键词:
造成的DNA损伤是DNA损伤.扩散型大B细胞淋巴瘤多发性骨髓瘤是多发性骨髓瘤的一种.突变的签名 突变的签名辐射辐射辐射辐射辐射辐射辐射辐射疗法 辐射疗法整个基因组的测序.

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