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Updated: Jun 13, 2026

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用多电极阵列对人类iPSC衍生的感觉神经元进行分析,用于止痛药物查.

Christian Fofie Kuete, Rafael Granja-Vazquez, Vincent Truong

    bioRxiv : the preprint server for biology
    |November 28, 2024
    PubMed
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    一个新的高含量查平台使用人类干细胞衍生的感受体来发现有效的止痛药物. 这种方法提高了药物测试的准确性,旨在减少将临床前发现转化为人类慢性疼痛治疗的失败.

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    相关概念视频

    EPS and iPS Cells in Disease Research01:21

    EPS and iPS Cells in Disease Research

    Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...