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Updated: Jun 6, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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增长因子和营养信号集成在mTORC1的溶酶体膜上的结构基础

Zhicheng Cui1,2, Alessandra Esposito3,4, Gennaro Napolitano3,4,5

  • 1Department of Molecular and Cell Biology, University of California Berkeley; Berkeley CA 94720, USA.

bioRxiv : the preprint server for biology
|November 28, 2024
PubMed
概括

拉巴胺素复合体1 (mTORC1) 在溶酶体膜上激活的机械标需要mTOR和Raptor与膜直接接触. 这个过程整合了生长因子和营养信号,实现了完全的催化激活.

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