从制药过程中获得的基于小麦的废弃物的化学表征,以其潜在的价值化
Lidia Ciriaco1, Luana Izzo1, Giulia Graziani1
1Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Frontiers in chemistry
|November 28, 2024
概括
富含酸和二酸的小麦加工废物没有细胞毒性. 这项分析支持将这些副产品作为宝贵的化品开发原料的再利用,促进循环经济.
科学领域:
- 农业科学 农业科学
- 分析化学 分析化学
- 生物技术是生物技术.
背景情况:
- 小麦 (Triticum vulgare) 的加工产生液体和固体废物.
- 这些副产品通常用于处置,这代表了潜在资源的损失.
- 农业废物的利用对于可持续的工业实践至关重要.
研究的目的:
- 分析和描述小麦加工废弃物,以便有可能重复使用.
- 评估这些废物流的生物特性,包括生物相容性和抗氧化活性.
- 确定利用废物开发新产品的可行性,特别是化品.
主要方法:
- 液体和固体废物的化学物理分析使用超高性能液体染色学与高分辨率轨道实验仪质谱学 (UHPLC-Q-Orbitrap HRMS) 相结合.
- 化合物的量化,特别是酸和二酸.
- 在人体皮肤细胞模型 (HaCaT和HDFa) 上进行体外生物相容性测试.
- 对抗氧化活性进行测试 (ABTS和FRAP).
主要成果:
- 酸 (89.782 mg/kg) 和二酸 (6.24 mg/L) 分别被确定为固体和液体废物的主要化合物.
- 固体废物提取物表现出显著的抗氧化活性 (ABTS为8.598毫米托洛克斯/千克,FRAP为7.262毫米托洛克斯/千克).
- 在暴露于废物提取物在高达100μg/mL的度下72小时的人类皮肤细胞中没有观察到细胞毒性作用.
结论:
- 小麦加工废物含有有价值的生物活性化合物,没有细胞毒性.
- 描述的废物适合作为化品行业的原料重复使用.
- 这种方法通过将废物转化为可回收资源来促进环保的循环经济.
相关概念视频
01:25Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
01:27Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
01:30Biological Treatment of Effluent and Waste Water
Biological wastewater treatment relies on the metabolic activity of microorganisms to remove pollutants from sewage. In modern treatment systems, this process is organized into sequential stages that progressively reduce solid material, dissolved organic matter, and microbial contamination. Each stage plays a distinct role in improving water quality and preparing the effluent for safe discharge or reuse.Primary and Secondary TreatmentPrimary treatment is a physical process that removes large...
01:25Biofuels
The microbial conversion of organic matter into biofuels holds potential as a renewable energy source. Among biofuel sources, microalgae are recognized as a highly efficient and adaptable feedstock for biodiesel production, owing to their rapid biomass accumulation, elevated lipid productivity, and capacity to proliferate in diverse aquatic systems, including freshwater, marine, and wastewater habitats. Unlike terrestrial crops, microalgae do not compete for land and can achieve significantly...
01:28Microbial Bioremediation of Plastics
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...
01:29Downstream Processing
Downstream processing begins once fermentation is complete and involves a series of steps to recover and purify products such as acids, vitamins, antibiotics, or proteins.Cell HarvestingFor example, for intracellular protein-based products, the first step is harvesting the cells. This is typically achieved using centrifugation or filtration to separate the cells from the liquid phase.Cell Disruption for Intracellular ProductsIf the target product is intracellular, the harvested cells must be...