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临床特征与周围产妇母体血流感染相关
Xiao-Li Gao1,2, Yang Li1,2, Su-Juan Hou1,2
1Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, China.
Frontiers in microbiology
|November 28, 2024
概括
在分娩期间发生的孕产妇血流感染 (BSI) 与皮膜过早破裂 (PROM) 和发烧有关. 早期发现病原体和抗生素耐药性对于预防母亲的严重后果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 孕产妇健康 孕产妇健康
背景情况:
- 产前血流感染 (BSI) 显著导致母亲的发病率和死亡率.
- 有限的数据存在于母亲的BSI在住院生育期间.
- 了解风险因素对于及时干预至关重要.
研究的目的:
- 调查母亲周产儿BSI的发病率,临床特征和危险因素.
- 分析微生物特征和抗生素耐药性模式.
- 确定皮膜过早破裂 (PROM) 和发烧在BSI发育中的作用.
主要方法:
- 发烧妇女在住院分娩期间进行血培养的回顾性分析.
- BSI (n=85) 和非BSI (n=361) 组之间的临床特征的比较.
- 鉴定致病原体,抗生素耐药性和结果.
主要成果:
- 在BSI组中,PROM,频繁的阴道检查和剖腹产更为普遍.
- 大肠杆菌是主要的病原体 (51.8%),具有显著的抗利沃素耐药性 (31.2%) 和ESBL产生 (38.6%).
- PROM,高发烧 (≥38.9°C) 和产后发烧被确定为BSI的危险因素.
结论:
- 孕产妇BSI是一种与PROM和发烧相关的严重疾病.
- 对病原体和抗微生物药物耐药性的监测对于预防孕产妇不良结果至关重要.
- 迅速识别和管理风险因素可以减轻BSI的严重性.
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