相关实验视频

Updated: Jun 6, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
09:19

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

4.8K

整合空间转录学和snRNA-seq数据可以增强AD相关表型的基因表达差异分析结果

Shizhen Tang, Shihan Liu, Aron S Buchman

    medRxiv : the preprint server for health sciences
    |November 28, 2024
    PubMed
    概括

    整合空间转录组学和单核RNA测序数据可以提高对阿尔茨海默病 (AD) 基因的发现. 这种方法识别了新的细胞类型特定的基因和途径,这对于理解AD病变发生和开发向疗法至关重要.

    更多相关视频

    Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq06:24

    Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

    Published on: March 12, 2021

    3.5K
    Identification of Alternative Splicing and Polyadenylation in RNA-seq Data08:35

    Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

    Published on: June 24, 2021

    5.4K

    相关概念视频

    RNA-seq03:21

    RNA-seq

    RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
    Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
    9.8K
    Ribosome Profiling02:24

    Ribosome Profiling

    Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
    Applications of ribosome profiling
    Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
    The technique...
    3.5K