身体活动与保持比率之间的关联 损伤的螺旋测量:一个横截面的NHANES研究
Xiaofang Fu1, JiangYing Guo2, Xiaofei Gu1
1The First People's Hospital of Hangzhou Linping District, Zhejiang University School of Medicine Second Affiliated Hospital Linping Hospital, Hangzhou, Zhejiang, People's Republic of China.
International journal of chronic obstructive pulmonary disease
|November 28, 2024
概括
参与定期的体力活动与降低患有保留比率减弱螺旋计 (PRISm) 的风险有关,这是慢性阻塞性肺病 (COPD) 的早期阶段. 这种关联对于身体质量指数 (BMI) 为25kg/m2或更高的人来说尤其强烈.
科学领域:
- 肺部医学 肺部医学
- 预防性健康 预防性健康
- 流行病学 流行病学
背景情况:
- 保存比例损伤螺旋计 (PRISm) 代表了慢性阻塞性肺病 (COPD) 的早期阶段.
- 关于有效的PRISM预防策略的研究有限.
- 了解可修改的风险因素,如身体活动,对于早期干预至关重要.
研究的目的:
- 调查身体活动水平与发展PRISm的风险之间的关联.
- 探索身体活动和PRISm之间的剂量反应关系.
- 为了确定特定的人口亚群,他们可能会从增加的身体活动中获益最多,以预防PRISm.
主要方法:
- 从国家健康和营养检查调查 (NHANES) (2007-2012) 中对美国成年人的横截面分析.
- 利用多变量逻辑回归和受限立方线 (RCS) 模型来评估这种关系.
- 检查的体力活动是每周的新陈代谢等效任务 (MET) 分钟.
主要成果:
- 与正常和COPD组相比,PRISm组表现出明显较低的身体活动水平.
- 较高的体力活动 (超过4800MET-min/周) 与PRISm的几率降低有关 (aOR=0.77,P=0.031).
- 在体力活动和PRISM风险之间观察到非线性,负的剂量反应关系 (P<0.05).
- 体重指数≥25公斤/平方米的个体显示,与较高的体力活动 (OR=0.51) 相关的PRISm风险明显较低.
结论:
- 增加体力活动与美国成年人群中PRISm风险较低有关.
- 身体活动对PRISm的保护作用在BMI≥25 kg/m2的个体中更为明显.
- 促进活跃的生活方式可以作为一种可行的预防措施,防止PRISm的发展.
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