与长间隔元素-1编码ORF1p相关的多个RNA结合蛋白被系统性红斑狼的自身免疫反应所准

Kennedy C Ukadike1,2, Alyssa N Colyer1, Bhargavi Duvvuri1

  • 1Division of Rheumatology, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

Journal of cellular and molecular immunology
|November 28, 2024
PubMed
概括

系统性红斑狼 (SLE) 患者对ORF1p和RNA颗粒中的其他八种蛋白质具有IgG自身抗体. 这些自身抗体与疾病活性和I型干扰素水平相关.

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