身体圆度指数轨迹和癌症风险:一个队列研究
Yue Chen1,2,3, Yiming Wang4, Xin Zheng1,2,3
1Department of Gastrointestinal Surgery, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Cancer medicine
|November 28, 2024
概括
高稳定的身体循环指数 (BRI) 轨迹与更高的癌症风险有关,特别是在中年男性和子宫癌中. 监测BRI变化对于健康指导至关重要.
科学领域:
- 肥胖研究的研究.
- 癌症流行病学癌症流行病学
- 生物识别分析 生物识别分析
背景情况:
- 身体圆周指数 (BRI) 是一种创新的肥胖指标,它结合了腰围和身高.
- 以前的研究忽视了BRI轨迹与癌症发病率之间的关系.
- 这项研究探讨了BRI轨迹与癌症风险之间的关联.
研究的目的:
- 调查身体圆指数 (BRI) 轨迹与癌症发病率之间的关联.
- 检查BRI轨迹与癌症风险之间的特定性别和特定年龄的关联.
- 探索BRI与特定地点癌症发病率之间的关系.
主要方法:
- 分析了42,022名参与者,追踪了2006-2010年的BRI变化.
- 确定了三种BRI轨迹模式 (低稳定,中稳定,高稳定).
- 考克斯回归分析被用来探索与癌症发病率和死亡率的关联,并进行了灵敏度分析.
主要成果:
- 高稳定的BRI轨迹与低稳定的轨迹相比,与癌症风险增加 (HR=1.46) 有关.
- 这种关联在中年男性和65岁以下的个人中更为明显.
- 高稳定的BRI轨迹与子宫癌发病率 (HR=4.92) 有着强烈的关联.
结论:
- 一个高度稳定的BRI轨迹与癌症发病率的增加密切相关,特别是在中年男性中.
- 高稳定的BRI轨迹与子宫癌的发展密切相关.
- 监测BRI值及其变化对于有效的健康指导和生活方式修改至关重要.
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