在患有癌症的人中,抵抗疲劳的抵抗训练
Moritz Ernst1, Carina Wagner1, Annika Oeser1
1Cochrane Haematology, Institute of Public Health, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
The Cochrane database of systematic reviews
|November 28, 2024
概括
抵抗训练可能会在癌症治疗期间改善与癌症相关的疲劳 (CRF) 和生活质量 (QoL). 虽然治疗后的效应显示了一些QoL益处,但长期数据有限,这突显了需要一致报告不良事件的必要性.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 康复 康复 康复 康复
背景情况:
- 癌症相关疲劳 (CRF) 是影响癌症患者福祉和治疗坚持的普遍症状.
- 运动干预措施,特别是阻力训练,显示出管理CRF的潜力,但证据综合仍然没有确定性.
- 以前的审查表明,关于抵抗训练在缓解CRF方面的有效性,有希望但不一致的发现.
研究的目的:
- 系统地评估抵抗训练对癌症患者CRF的影响.
- 为了在不同治疗阶段 (治疗前,治疗期间,治疗后) 和随访期内比较抵抗训练与不训练.
- 评估对生活质量 (QoL),不良事件,抑郁和焦虑的影响.
主要方法:
- 在八个数据库 (如CENTRAL,Medline,Embase) 进行了广泛的文献搜索,截至2023年10月.
- 包括21项随机对照试验 (RCT),涉及2221名成人癌症患者,比较了抵抗训练和没有训练.
- 分析了短期 (≤12周),中期 (>12周至<6个月) 和长期 (≥6个月) 的影响,使用柯克兰方法和GRADE以确定证据.
主要成果:
- 在治疗期间:抵抗训练可能会改善短期的CRF (中等确定性),并可能对短期的QoL (低确定性) 带来小益处.
- 治疗后:抵抗训练可能对短期QoL (低确定性) 带来很小的益处,对短期CRF的影响非常不确定.
- 关于CRF和QoL的中长期影响以及不良事件的证据仍然非常不确定,因为数据有限或稀疏.
结论:
- 耐力训练表明,在癌症治疗期间服用CRF和QoL可能会对CRF和QoL产生短期益处.
- 治疗后的耐力训练可能会在短期的QoL中略有改善,但缺乏可靠的长期数据.
- 在所有研究部门中对不良事件的一致和完整报告对于未来的证据综合至关重要.
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